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. Author manuscript; available in PMC: 2015 Jan 22.
Published in final edited form as: J Am Chem Soc. 2014 Jan 8;136(3):854–857. doi: 10.1021/ja410958j

Figure 1.

Figure 1

(Left) Schematic of C99 showing key sequence information, likely secondary structure regions, ∊- and γ- cleavage sites, and approximate insertion within the membrane bilayer. The break in the TM helix at the “GG kink” between G37/G38 is indicated. (Right) Depiction of C9915–55 monomer in a POPC lipid bilayer (above) showing an average tilt angle of 22.5 (deg) with respect to the bilayer normal and (below) C9915–55 in a DPC micelle. The phosphocholine group is shaded green (POPC) or yellow (DPC).