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. 2014 Feb 18;9(2):e87644. doi: 10.1371/journal.pone.0087644

Table 1. Cells expressing AQP either exogenously or endogenously are resistant to ultra-quick freezing/thawing.

Cell lines Expression of AQP4 Cell viability ± S.D. (%)
CHO (-) 2.4±1.4
AQP4 60.5±16.7
MDCK (-) 0.7±0.8
AQP4 37.2±8.7
Astrocytes AQP4 KO 2.5±2.3
WT 54.1±6.4

Cell viability after ultra-quick freezing/thawing: comparison between CHO, MDCK cells and stably expressing AQP4 cells (AQP4-CHO, AQP4-MDCK), and also primary culture astrocytes from WT-mice (AQP4+) or AQP4-null mice (n ≧ 3, ***P<0.001).