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. Author manuscript; available in PMC: 2014 Feb 18.
Published in final edited form as: ACS Chem Biol. 2013 Oct 16;8(12):2785–2793. doi: 10.1021/cb400607h

Figure 3. CaCRG1 is important for cantharidin-perturbed morphogenesis and membrane trafficking in C. albicans.

Figure 3

A. Transcriptional profile of wt grown in the presence of cantharidin. GO Biological Term Enrichment was applied to significantly (P-value<0.05) downregulated genes (log2 (drug/DMSO) >|2|).

B. qRT-PCR analysis demonstrates that CaCRG1 is a cantharidin-responsive gene. Data are means of at least three independent experimental replicates, and error bars are SD.

C. cacrg1Δ/Δ has reduced adherence to plastic surface in the presence and absence of cantharidin. *P-value <0.05, ** <0.01.

D. cacrg1Δ/Δ fails to form hyphae in the presence of cantharidin.