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. Author manuscript; available in PMC: 2014 Feb 18.
Published in final edited form as: ACS Chem Biol. 2013 Oct 16;8(12):2785–2793. doi: 10.1021/cb400607h

Figure 6. CaCrg1 is important for sphingolipid biosynthesis.

Figure 6

A. Fitness of double deletion mutants in liquid SC media at 39°C.

B. CaCRG1 interacts with GlcCer genes in a condition-dependent manner. The unexpected phenotypes for double mutants (relative to wt and crg1Δ/Δ mutant) are highlighted: “+” denotes positive genetic interactions, “-“ denotes negative genetic interaction.

C. Adherence of cacrg1Δ/Δsld1Δ/Δ to abiotic surface.

D. Abundance of ceramide-related species in cacrg1Δ/Δ and wt. Statistically significant difference in the abundance (Student’s t-test) is shown in red. Error bars are standard deviation. *P-value<0.05, **P-value<0.1, Student’s t-test.