Table 4. Gastric microbiota studies in Mongolian gerbils.
| Study | Method | # of Samples | Age | Sex | HP status | Phyla | Genus information | HP effect |
|---|---|---|---|---|---|---|---|---|
| Sun et al. 2003 | TTGE/NGS-sequenced 16S rDNA library | 5 | 5 wk old + 12 wk | Male | Uninfected | Firmicutes, Proteobacteria | Firmicutes (Lactobacillus) (82.4%), and Proteobacteria (Pseudomonas), Proteobacteria (Acinetobacter), Firmicutes (Bacillus, Enterococcus, Paenibacillus) (17.6%) | No info on levels, just identification |
| 5 | 5 wk old + 12 wk infection | Male | HP ATCC 43504 | Firmicutes, Proteobacteria, Actinobacteria | Firmicutes (Lactobacillus) (51.7%), Proteobacteria (Helicobacter pylori) (37.1%) and Proteobacteria (Pseudomonas, Acinetobacter), Actinobacteria (Corynebacterium), Firmicutes (Enterococcus, and Staphylococcus) (11.2%) | Severe chronic active gastritis | ||
| Zaman et al. 2010 | Culture + API | 1 | 5 wk old + 8 wk infection | Female | H pylori TK1042 (low detection) | Firmicutes, Proteobacteria, Actinobacteria | Firmicutes (Lactobacillus), Proteobacteria (Escherichia, Kluyvera), Actinobacteria (Bifidobacterium, Actinomyces) | Based on culture of single gerbil. Altered obligate anaerobe composition. |
| 1 | 5 wk old + 8 wk infection | Female | H pylori TK1402 (high detection) | Firmicutes, Proteobacteria, Actinobacteria | Firmicutes (Eubacterium), Proteobacteria (Escherichia, Kluyvera), Actinobacteria (Bifidobacterium, Actinomyces) | |||
| Yin et al. 2011 | Culture | 8 | 6–8 wk old + 12 wk | Male/ Female | Uninfected | Firmicutes, Actinobacteria | Firmicutes(Lactobacillus), Actinobacteria (Bifidobacterium) | |
| 3 | 6–8 wk old + 12 wk infection | Male/ Female | HP J99 | Firmicutes, Actinobacteria, Bacteroidetes | Observed new species and shifts in microbiota | Observed Bacteroidetes (Bacteroides) and Firmicutes (Enterococcus). Trend of increasing Actinobacteria (Bifidobacterium). Increased gastritis | ||
| Osaki et al. 2012 | qPCR | 5 | 8 wk old + 1 y | Male | Uninfected | Firmicutes, Actinobacteria | Actinobacteria (Atopobium spp, Bifidobacterium spp), Firmicutes (Clostridium coccoides, C. leptum, Enterococcus spp and Lactobacillus spp) | |
| 5 | 8 wk old + 1 y infection | Male | HP positive | Firmicutes, Actinobacteria | Actinobacteria (Atopobium spp, Bifidobacterium spp), Firmicutes (Clostridium coccoides, C. leptum, Enterococcus spp and Lactobacillus spp) | vs. uninfected - lower Clostridium coccoides | ||
| 6 | 8 wk old + 1 y infection | Male | HP negative | Firmicutes, Actinobacteria, Bacteroidetes | Actinobacteria (Atopobium, Bifidobacterium), Firmicutes (Clostridium, Enterococcus, Lactobacillus, Eubacterium) and Bacteroidetes(Prevotella) | vs. uninfected -lower Clostridium and Bifidobacterium. Higher Atopobium |
*
N/A, Not available