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A. CONSORT flowchart of subject enrolment. B. After an initial screening visit, blood and gut mucosal biopsies were obtained 28 and 14 days before initiation of vaccination. Vaccinations (vCP205 or placebo) were administered Days 0, 7, 14, 21. Blood samples then were collected on Days 10, 17, 24, 180, and 360. Gut mucosal biopsies were collected at Days 10, 24, 180, 360.
