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. 2014 Feb 18;9(2):e88706. doi: 10.1371/journal.pone.0088706

Table 4. Validation analysis of u-FCMSS in the second cohort including MDS and non-clonal cytopenias diseases.

Conventional diagnosis (clinical and morphologic diagnosis)
MDS Non-clonal cytopenias Total
u-FCMSS diagnosis MDS 78 (a) 3 (b) 81 (a+b)
Non-MDS 12 (c) 42 (d) 54 (c+d)
total 90 (a+c) 45 (b+d)

Sensitivity = [a/(a+c)]×100% = 86.7%.

Specificity = [d/(b+d)]×100% = 93.3%.

Positive predictive value = [a/(a+b)]×100% = 96.3%.

Negative predictive value = [d/(c+d)]×100% = 77.8%.

Diagnosis agreement rate = [(a+d)/(a+b+c+d)]×100% = 88.9%.