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. 2014 Feb 18;9(2):e88734. doi: 10.1371/journal.pone.0088734

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© 2014 Sherwani et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Distribution of anti-MC084S antibodies in a UK population tested by direct binding ELISA. (A) Serological responses to MCV antigen MC084S (V123-R230) in UK population (n = 79) expressed as the δODU value of an individual serum sample in different groups (i) Primary progressive multiple sclerosis (PPMS; n = 9), (ii) Relapsing remitting multiple sclerosis (RRMS; n = 33) and (iii) Healthy humans (n = 37). The horizontal bar within each group represents the median absorbance measurement (B) Percent positivity in individual groups for MC084S after cut-off of 0.36 (i) PPMS (11.1%), (ii) RRMS (16.2%) and (iii) healthy humans (30.3%).