Table 3. Geometric mean concentrations (GMC) of IgG antibodies against pertussis toxin, filamentous hemagglutinin and pertactin in 213 infant subjects with MBL wild type (A/A), heterozygotes variant type A/O (A/B, A/C, A/D) and homozygote variant type O/O (B/B, D/D, C/B) at age of 2,5 months, 13 months and 2 years.

	MBL A/A		MBL A/O		MBL O/O		P-value*
Pertussis toxin	n	GMC (95% CI)	n	GMC (95% CI)	n	GMC (95% CI)
2.5 months	45	0.8 (0.5 – 1.2)	24	1.1 (0.6 – 2.1)	3	1.1 (0.6 – 2.1)	0.39
13 months	147	50.7 (43.4 – 59.2)	60	42.2 (29.2 – 60.9)	4	69.8 (37.0 – 131.6)	0.75
2 years	78	6.8 (5.3 – 8.6)	28	6.8 (4.2 – 11.1)	2	4.9 (0.4 – 64.4)	0.71
Pertactin
2.5 months	45	1.8 (1.1 – 3.2)	24	2.6 (1.5 – 4.5)	3	2.0 (0.1 – 38.7)	0.73
13 months	147	38.5 (26.3 – 56.4)	60	26.9 (14.2 – 50.8)	4	70.0 (8.1 – 604.4)	0.48
2 years	78	7.1 (4.8 – 10.5)	28	7.7 (4.2 – 14.5)	2	16.3 (7.5 – 35.5)	0.78
Filamentous hemagglutinin
2.5 months	45	1.8 (1.0 – 3.3)	24	3.6 (2.0 – 6.7)	3	2.2 (0.3 – 16.0)	0.43
13 months	147	164.4 (142.7 – 189.4)	60	145.7 (102.0 – 208.0)	4	203.6 (135.1 – 306.9)	0.88
2 years	78	32.6 (26.9 – 39.5)	28	36.4 (24.1 – 54.7)	2	12.0 (12.0 – 12.0)	0.19

Abbreviations: GMC, geometric mean concentration; CI, confidence interval; *Kruskal-Wallis test for comparison of antibody concentrations between genotypes A/A, A/O and O/O. P-value <0.05 is considered as statistically significant.