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. 2014 Feb 18;9(2):e89306. doi: 10.1371/journal.pone.0089306

Table 1. Distribution of mutations with regards to NA subtype.

NA No. of isolates (x) Mutation No. of mutants (y) % (y/x)
N1 R118K 1 2.6
R118K D151N 1 2.6
R118K D151N D198N 1 (3) 1) 2.6 (7.7)4)
D151K 1 2) 2.6
I222V 1 2.6
All 39 5 12,8
N2 - 0 0.0
All 77 0 0.0
N3 R118K 1 3) 4.4
R156K 1 2) 8.7
All 23 3 13.0
N5 R118K R152K D198N 1 3) 8.3
All 12 1 8.3
N6 R152K 6 (2) 3) 10.9
All 55 6 10.9
N8 - 0 0.0
All 13 0 0.0
N9 R118K 2 13.4
R118K D151N 1 7.7
All 11 3 27.3
Total 230 18 (15) 4) 7.4 (6.5) 4)

Mainly adopted from Orozovic et al. [26].

1)

Sum of all R118K mutations.

2)

Mutation unrelated to inhibitor resistance.

3)

Isolates that were not analyzed.

4)

Previously published values.