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. 2014 Feb 18;9(2):e89154. doi: 10.1371/journal.pone.0089154

Figure 1. ROI-based measurement of T2-signal intensity of muscle, peroneal and tibial division of the sciatic nerve.

Figure 1

siMR neurographic T2-weighted images with fat-saturation (a, b, c). Exemplary ROI-based analysis of signal intensities of the peroneal and tibial portion of the sciatic nerve, the normal appearing musculature, and background noise in patient 5 (a), patient 1 (b) and a healthy control (c). In (a), a distinctive T2-signal increase of the peroneal and tibial nerve in patient 5, and in (b) a T2-signal increase of peroneal division of the sciatic nerve in patient 1 are shown. In the healthy control no pathological nerve signal increase is present (c). In (d) the corresponding SR of the peroneal and tibial portion of the sciatic nerve are shown. In the healthy control, and in the normal appearing tibial portion of the sciatic nerve in patient 1 SR are below 1.7. A SR above 1.7 indicates a lesion of the peroneal portion of the sciatic nerve in patient 1, and in the peroneal and tibial portion of the sciatic nerve in patient 2 (d). Abbreviations: p: peroneal portion of the sciatic nerve or peroneal nerve; SR: nerve-to-muscle T2- signal intensity ratio; t: tibial portion of the sciatic nerve or tibial nerve.