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. 2014 Feb 18;9(2):e89491. doi: 10.1371/journal.pone.0089491

Figure 3. Scratch wounding assays demonstrating accelerated wound closure after Dsg2 depletion.

Figure 3

Confluent monolayers of Dsg2-depleted (“Dsg2 Ko”) or non-targeting siRNA-treated (“nt Ko”) MeWo were wounded by scratching. (A) Bar diagram showing the percental width of the wound cleft at different time points after scratching. (B) Representative micrographs of wound clefts taken 0, 8, 16 and 24 h after scratching. Bars: 200 µm. (C) Scratch wounding experiment of Dsg2-depleted and non-targeting siRNA-treated MeWo cells that had been preincubated with mitomycin C to abolish proliferation. Bars: SD; * p≤0.05, ** p≤0.01, *** p≤0.001.