Table 3.
Multivariate Cox analyses of the high-TC, intermediate-TC, and low-TC groups for total mortality without adjustment; with adjustment only for gender; and with adjustment for gender; smoking, alcohol intake, history of stroke or heart disease, serum albumin concentration, BMI, and systolic BP
| Hazard ratio | 95% CI | P-value | |
|---|---|---|---|
| Not adjusted | |||
| High TC | 1.000 | ||
| Intermediate TC | 1.445 | 0.904–2.311 | 0.124 |
| Low TC | 2.361 | 1.494–3.732 | 0.000 |
| Adjusted only for gender | |||
| High TC | 1.000 | ||
| Intermediate TC | 1.298 | 0.807–2.087 | 0.283 |
| Low TC | 2.042 | 1.278–3.262 | 0.003 |
| Men | 1.786 | 1.229–2.596 | 0.002 |
| Women | 1.000 | ||
| Adjusted for gender, smoking, alcohol intake, history of stroke and heart disease, serum albumin concentration, BMI, and systolic BP | |||
| High TC | 1.000 | ||
| Intermediate TC | 1.133 | 0.670–1.914 | 0.642 |
| Low TC | 1.718 | 1.016–2.906 | 0.044 |
| Men | 1.672 | 1.110–2.520 | 0.014 |
| Women | 1.000 | ||
| Nonsmoker | 1.000 | ||
| Smoker | 1.304 | 0.606–2.806 | 0.498 |
| Nondrinker | 1.000 | ||
| Drinker | 0.877 | 0.597–1.288 | 0.504 |
| History of stroke (+) | 1.240 | 0.586–2.627 | 0.574 |
| History of stroke (−) | 1.000 | ||
| History of heart disease (+) | 1.177 | 0.754–1.837 | 0.472 |
| History of heart disease (−) | 1.000 | ||
| Albumin concentration (g/dL) | 0.491 | 0.232–1.041 | 0.064 |
| BMI (kg/m2) | 0.939 | 0.883–0.998 | 0.044 |
| Systolic BP (mmHg) | 0.997 | 0.989–1.004 | 0.389 |
Note: The TC group was divided into three groups (high ≥209 mg/dL; intermediate 176–208 mg/dL; low ≤175 mg/dL), in relation to serum TC concentration.
Abbreviations: BMI, body mass index; BP, blood pressure; CI, confidence interval; TC, total cholesterol.