Skip to main content
. Author manuscript; available in PMC: 2015 Jan 16.
Published in final edited form as: Cell. 2014 Jan 16;156(0):109–122. doi: 10.1016/j.cell.2013.12.018

Figure 3. Foxo activation in aging intestines activates IMD/Rel signaling.

Figure 3

A) Expression of Foxo target genes Lip4 and InR in axenically and conventionally reared animals as determined by RNASeq (lines) and qRT-PCR (for InR, relative to actin5C, bars). Averages and standard deviations (N=3; ** p<0.01, Student’s Ttest).

B) X-Gal staining showing activation of thor-lacZ in aging intestines.

C) qRT-PCR detecting Rel and Dpt expression relative to actin5C in wild-type (OreR) or foxoW24 aged axenically. Averages and standard deviations (N>=3; p values from Student’s Ttest).

D) qRT-PCR detecting Dpt expression relative to actin5C in animals expressing FoxoRNAi using NP1∷Gal4 in w1118 (left) or y1w1 (right) backgrounds and aged conventionally. Averages and standard deviations (N>=3; p values from Student’s Ttest).

See also Figure S3.