Skip to main content
. Author manuscript; available in PMC: 2014 Mar 3.
Published in final edited form as: Circulation. 2012 Oct 3;126(15):1882–1895. doi: 10.1161/CIRCULATIONAHA.112.113290

Figure 5. Effect of CXCL12 isoforms on post-ischemic revascularization.

Figure 5

Quantitative evaluation of foot perfusion (A), microangiography (B), capillary density (C), and arteriolar density (D) and macrophages infiltration (E), 21 days after ischemia in C57BL/6 mice transfected with empty DNA plasmid (CONT) or DNA expression vectors encoding CXCL12α, CXCL12γ or CXCL12γm2. Values are mean ± SEM. n = 15 per group, representative of 3 independent experiments. A–B) 6 possible comparisons for Bonferroni correction, a value of p<0.008 was considered significant, *p<0.008, **p<0.0016 versus PBS, † p<0.008 versus CXCL12α, #p<0.008, ##p<0.0016 versus CXCL12γ. C–E) 28 possible comparisons for Bonferroni correction, a value of p<0.0017 was considered significant, *p<0.0017 versus Isc CONT, †p<0.0017 versus Isc CXCL12α, #p<0.0017 versus Isc CXCL12γ. Isc indicates ischemic leg and N.Isc, non ischemic leg.