Figure 1.

Ten PET100 Individuals from Eight Families of Lebanese Ancestry

(A) Pedigrees of the eight Lebanese families. Double horizontal line indicates consanguinity. Squares and circles represent males and females, respectively. Diamonds indicate gender is unknown. Black symbols represent affected individuals and diagonal lines denote deceased individuals. Grey symbols represent children who died without investigation and remain undiagnosed.

(B) A map of Lebanon with red pins marking the regions of origin of the parents in families B, C, D, E, G, and H. Scale bar represents 20 km.

(C) Summary of the complementation analysis based on galactose sensitivity of fused cell lines. “A1–F1” and “SURF1” indicate fibroblast cell lines from the Lebanese LS and SURF1 individuals, respectively. 143B ρ° cell line does not contain mtDNA. Y and X indicate positive and negative complementation in galactose media, respectively.