Fig. 4.

Cytokine profile of monocyte-derived dendritic (mo-DCs) cells pre- and post-lipopolysaccharide (LPS) stimulation. Secretion of IL1β, IL12 and TNF-α increased significantly in LPS stimulated mo-DCs after therapy in SVR+ patients, although those from SVR-patients secreted high IL10 before and after therapy. HC, healthy controls; SVRO+, treatment naïve sustained virological responders; SVR6+, responders post 6 months treatment; SVR6-, non-responders post 6 months treatment.

(Reproduced with permission from John Wiley and Sons Ltd., Philadelphia, USA [Liver Int 2012; 32 : 1128-37]68.