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. Author manuscript; available in PMC: 2014 Nov 15.
Published in final edited form as: ACS Chem Biol. 2013 Sep 13;8(11):2501–2508. doi: 10.1021/cb400400j

Figure 1.

Figure 1

Description of PAN structure. (A) APBS51 calculated electrostatic potential surface of the active site cleft of PAN. The binding of a ligand described in this study (7) is shown with yellow carbon atoms and a carboxamide derivative with three chelating groups crystallized by Dubois et al. is shown in gray (PDB code: 4E5I).19 The subpockets are labeled as previously described.19 (B) Superposition of the pH1N1 2009 PAN structures from this study and one previously described (PDB code: 4AVQ).18