Figure 12.

Gap junctions in cornea. (A) In normal intact cornea, gap junction connexin 43 (Cx43) (green) was present in the basal cell layer of the corneal epithelium. Basement membrane protein laminin (red) was found in the basement membrane region beneath the epithelium. Scale bar 50 μm. (B) Twelve hours after wounding, Cx43 and laminin were present in low levels at the back of the migrating epithelium (white arrow), but not at the leading edge (left). Black arrowhead shows original site of wound edge. Scale bar 50 μm. Reprinted with permission from Suzuki et al.⁹² To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/wound