Table 3.
Gene | SNP | Minor allele | MAF | P* | |||||
---|---|---|---|---|---|---|---|---|---|
DM | HT | DM + HT | Control subjects | DM | HT | DM + HT | |||
LEPR | rs12037879 | A | 0.210 | 0.228 | 0.216 | 0.162 | 0.13 | 0.041 | 0.10 |
LEPR | rs7554485 | C | 0.082 | 0.110 | 0.090 | 0.108 | 0.36 | 1.00 | 0.54 |
LEPR | rs1137100 | A | 0.153 | 0.144 | 0.172 | 0.186 | 0.34 | 0.22 | 0.72 |
LEPR | rs13306519 | G | 0.206 | 0.191 | 0.192 | 0.138 | 0.024 | 0.07 | 0.07 |
LEPR | rs1137101 | A | 0.133 | 0.135 | 0.100 | 0.128 | 0.63 | 0.82 | 0.32 |
LEPR | rs8179183 | C | 0.057 | 0.062 | 0.074 | 0.043 | 0.53 | 0.41 | 0.17 |
ADIPOQ | rs16861194 | G | 0.170 | 0.164 | 0.163 | 0.185 | 0.62 | 0.49 | 0.47 |
ADIPOQ | rs266729 | G | 0.259 | 0.343 | 0.266 | 0.27 | 0.73 | 0.042 | 0.93 |
ADIPOQ | rs12495941 | T | 0.421 | 0.374 | 0.408 | 0.382 | 0.34 | 0.88 | 0.52 |
ADIPOQ | rs2241766 | G | 0.286 | 0.282 | 0.269 | 0.256 | 0.39 | 0.45 | 0.73 |
ADIPOQ | rs1501299 | A | 0.279 | 0.254 | 0.276 | 0.275 | 0.93 | 0.54 | 1.00 |
ADIPOQ | rs1063537 | T | 0.268 | 0.436 | 0.310 | 0.363 | 0.014 | 0.06 | 0.19 |
ADIPOQ | rs12629945 | A | 0.215 | 0.226 | 0.179 | 0.218 | 1.00 | 0.84 | 0.29 |
ADIPOQ | rs6444175 | A | 0.280 | 0.261 | 0.277 | 0.278 | 1.00 | 0.67 | 1.00 |
RETN | rs2161490 | T | 0.390 | 0.431 | 0.439 | 0.424 | 0.35 | 0.88 | 0.76 |
RETN | rs3745368 | A | 0.153 | 0.150 | 0.145 | 0.134 | 0.51 | 0.59 | 0.74 |
TRIB3 | rs12626158 | A | 0.222 | 0.248 | 0.247 | 0.213 | 0.85 | 0.29 | 0.35 |
TRIB3 | rs6051637 | T | 0.227 | 0.175 | 0.185 | 0.19 | 0.25 | 0.62 | 0.92 |
TRIB3 | rs6115830 | T | 0.303 | 0.324 | 0.292 | 0.346 | 0.25 | 0.58 | 0.16 |
TRIB3 | rs2295491 | A | 0.108 | 0.151 | 0.130 | 0.15 | 0.13 | 1.00 | 0.49 |
TRIB3 | rs2295492 | C | 0.169 | 0.178 | 0.149 | 0.186 | 0.61 | 0.84 | 0.20 |
TRIB3 | rs6037542 | T | 0.286 | 0.347 | 0.320 | 0.331 | 0.24 | 0.69 | 0.80 |
Significant SNPs and P values are shown in bold type
DM represents type 2 diabetes, HT represents hypertension
* Obtained from Fisher’s exact test versus control subjects