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. 2013 Nov 7;23(6):1506–1515. doi: 10.1093/hmg/ddt537

Figure 5.

Figure 5.

Lmnaplao-5nt/plao-5nt and Lmnaplao-utr/plao-utr mice have no detectable neuropathology. (A and B) Brains from 1-month-old Lmna+/+ (+/+), Lmnaplao-5nt/+ (5NT/+), Lmnaplao-5nt/plao-5nt (5NT/5NT), Lmnaplao-utr/+ (UTR/+) and Lmnaplao-utr/plao-utr (UTR/UTR) mice, viewed from the top. Scale bar, 5 mm. (C and D) Immunofluorescence microscopy of the cerebral cortex from 1-month-old Lmnaplao/plao (PLAO/PLAO), Lmnaplao-5nt/plao-5nt (5NT/5NT), Lmnaplao-utr/plao-utr (UTR/UTR) and wild-type (+/+) littermate mice stained with antibodies against Cux1 (red) and Ctip2 (green) (C) or NeuN (white) (D). Scale bar, 100 µm.