Table 3. Enzyme-Inhibitory Activities and Antiproliferative Activities of Compounds 1–3 and 9^a.

	IC50 (μM)				GI50 (μM)
compd	KDM2A	KDM7A	KDM7B	KDM4C	KYSE150	HeLa
1	45	>250	>250	>250	>240	>710
2	4.1	15	>250	8.2	>240	>240
3	0.20	1.6	19	2.2	>470	>470
9	6.8	0.20	1.2	83	16	40

^aValues are means of two experiments that in all cases varied by 30% or less.