Table 3.
Response of follicular hormones and ovarian follicle growth to ovarian stimulation in control (n= 5) and obese (n= 4) Ossabaw pigs
| Stage of superovulation protocol |
|||||||
| Initial | 1st third | 2nd third | Last third | 1 d after hCG | 2 d after hCG | ||
| Testosterone (ng/mL) | Control | 0.6 ± 0.3 | 0.6 ± 0.3 | 1.0 ± 0.3 | 1.3 ± 0.3 | 1.2 ± 0.3 | 1.5 ± 0.3 |
| Obese | 0.6 ± 0.4 | 0.7 ± 0.4 | 1.6 ± 0.4 | 1.7 ± 0.4 | 1.5 ± 0.4 | 1.5 ± 0.3 | |
| Androstenedione (ng/mL) | Control | 0.8 ± 1.8 | 1.1 ± 1.5 | 2.4 ± 1.5 | 3.2 ± 1.5 | 2.7 ± 1.5 | 2.5 ± 1.5 |
| Obese | 0.8 ± 2.0 | 1.3 ± 2.0 | 4.8 ± 2.0 | 8.5 ± 2.0 | 6.0 ± 2.0 | 3.9 ± 2.0 | |
| Estradiol (pg/mL) | Control | 10.6 ± 68.1 | 24.1 ± 56.3 | 68.6 ± 56.3 | 69.3 ± 56.3 | 67.0 ± 56.3 | 59.3 ± 60.0 |
| Obese | 13.3 ± 112.2 | 29.6 ± 72.7 | 151.4 ± 72.7 | 241.2 ± 72.7 | 66.6 ± 72.7 | 47.3 ± 72.7 | |
| Progesterone (ng/mL) | Control | 1.6 ± 0.5 | 1.4 ± 0.4 | 2.0 ± 0.6 | 4.1 ± 2.3 | 4.5 ± 3.0 | 10.8 ± 7.9 |
| Obese | 1.7 ± 0.5 | 1.3 ± 0.5 | 2.1 ± 0.7 | 4.1 ± 3.0 | 5.2 ± 3.8 | 21.6 ± 10.2 | |
| Ovulatory size follicles | Control | 1.5 ± 0.7 | 0.7 ± 1.0 | 7.1 ± 3.0 | 17.7 ± 11.6 | 21.1 ± 10.2 | 17.0 ± 7.4 |
| Obese | 0.5 ± 0.8 | 1.4 ± 1.2 | 15.4 ± 3.4 | 34.6 ± 13.4 | 39.8 ± 11.8 | 12.2 ± 8.5 | |
| Postovulatory size follicles | Control | 0.0 ± 1.5 | 0.0 ± 1.5 | 0.0 ± 1.5 | 1.6 ± 1.5 | 2.5 ± 1.5 | 3.4 ± 1.5a |
| Obese | 0.0 ± 1.7 | 0.0 ± 1.7 | 0.0 ± 1.7 | 0.0 ± 1.7 | 5.1 ± 1.7 | 8.8 ± 1.7b | |
a,bValues are significantly (P = 0.04) different.