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. 2014 Feb;64(1):50–54.

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Figure 3. — AntiHBsAg IgG1, IgG2a, and IgM titers in immunized minipigs after various routes of vaccine administration. The numbers of responding animals per total numbers of immunized animals are depicted above the titer dots. (A) IgG titers of minipigs on days 14 and 28 after priming and booster immunization with HBsAg intramuscularly by needle (IM-needle) and intradermally by needle (ID-needle) and DSJI (ID-DSJI). (B) IgG1 and IgG2a titers in minipigs on day 28 after priming and booster immunization with HBsAg. (C) IgM titers of minipigs on days 14 and 28 after priming and booster immunization with HBsAg intramuscularly by needle and intradermally by needle and DSJI.