Skip to main content
. Author manuscript; available in PMC: 2015 Jan 15.
Published in final edited form as: Bioorg Med Chem Lett. 2013 Nov 28;24(2):674–678. doi: 10.1016/j.bmcl.2013.11.049

Table 3.

SAR of the 1,2,4-oxadiazole group of NS9283

Compound Structure PAM(Y or N)a EC50 (uM) Emaxb
5a graphic file with name nihms551756t19.jpg N — —
5b graphic file with name nihms551756t20.jpg N — —
5c graphic file with name nihms551756t21.jpg N — —
5d graphic file with name nihms551756t22.jpg N — —
5e graphic file with name nihms551756t23.jpg N — —
5f graphic file with name nihms551756t24.jpg N — —
5g graphic file with name nihms551756t25.jpg N — —
5h graphic file with name nihms551756t26.jpg N — —
5i graphic file with name nihms551756t27.jpg N — —
5j graphic file with name nihms551756t28.jpg N — —
5k graphic file with name nihms551756t29.jpg Y 2.0±0.9 2.5
a,b

See Table 1 caption.