FIG. 4.

Chondrogenic capacity of fetal and adult MSCs. Micromass pellet cultures were treated with transforming growth factor beta 3 (TGFβ3) and BMP2, alone and in combination for 21 days. The relative expression of chondrogenic marker genes and hypertrophic marker genes were measured using real-time qPCR analyses and are expressed relative to an undifferentiated control and normalized to beta actin. Each line is the mean±SEM (n=4), *P<0.05, **P<0.01 by Kruskal–Wallis with a Dunn's post-hoc correction for multiple comparisons.