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Oxidative stress parameters of streptozotocin-induced diabetic rats: AOPP levels (a), nitric oxide levels (b), superoxide dismutase (SOD) (c), and catalase activity (CAT) activity (d). Data are expressed as mean ± SEM (n = 6 per group). ANOVA followed by Duncan's test: *P < 0.05 versus nondiabetic control; # P < 0.05 versus diabetic vehicle. BIX 10: 10 mg/kg bixin; BIX 100: 100 mg/kg bixin; NBIX 10: 10 mg/kg norbixin; NBIX 100: 100 mg/kg norbixin.
