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Model for oriented cell division.
Note: Members of the Par complex and Dlg interact with LGN to anchor spindle poles to the lateral membranes.
Abbreviations: aPKC, atypical protein kinase C; cdc42, cell division control protein 42; Dlg, Discs-large; E-cad, E-cadherin; LGN, Leu-Gly-Asn repeat-enriched protein; NuMA, nuclear mitotic apparatus protein; MT, microtubule; Gαi, guanine nucleotide binding protein alpha inhibitory 1.
