Figure 5. Time-averaged phosphoflow data of Stat proteins sorted by cell type and NAb class.

Visualization of ffMANOVA and ANOVA results with pivot tables graphs. Phosphoflow data (stimMFI/unstimMFI) for every patient for every cell subtype was averaged for time points t₄, t₆, and t₈. The main factor, time of sample collection, did not affect the phosphoflow data significantly. The importance of pStat1 and pStat4 in NAb class identification are clearly visible. M: CD33⁺ monocytes; T3: CD3⁺ T cells; T4: CD3⁺CD4⁺ T cells; T8: CD3⁺CD8⁺ T cells; B: CD20⁺ B cells; L: lymphocytes, NK: CD94⁺ NK cells. Granulocytes are not shown. MFI: median fluorescent intensity.