Table 1. Patient characteristics.

Patient Identification number	Sex	Age	Disease onset	EDSSa	Treatment duration (years)	IFN-β preparation	NAb levelsb
106	F	39	2003	0	3	IFN-β-1a s.c.	High
						Rebif
108	F	40	1999	1	5	IFN-β-1b s.c.	High
						Betaferon
109	M	45	1984	2	3	IFN-β-1b s.c.	Neg.
						Extavia
110	F	37	1998	2,5	1	IFN-β-1b s.c.	Neg.
						Extavia
111	F	44	2002	2	3	IFN-β-1a s.c.	Neg.
						Rebif
112	F	49	2001	4	2	IFN-β-1a s.c.	Med.
						Rebif

^aExpanded Disability Status Scale score.

^bNAb titers were measured in sera of patients by the Mx1 induction assay.