Figure 1. Binding of XMetD to the A and B isoforms of the INSR by FACS. Intact CHO-hINSR cells expressing either the A or B isoform of the INSR were incubated for 120 min at 15 °C with increasing concentrations of XMetD. XMetD binding to the INSR was measured by flow cytometry (FACS). Mean ± SD of triplicate determinations are shown.