Table 1. Nicotine administration and food-restriction have effects on pregnancy and birth characteristics.
| Measure | Timing | F | P-value | Con | Nic | Con-Pf |
| Dams | ||||||
| Mean body weight | Week before pregnancy | 12.38 | 2.50E-04 | 252.2±6.2 | 213.9±6.5* | 223.4±4.1* |
| (g) | Pregnancy | 13.30 | 1.63E-04 | 289.1±6.7 | 247.8±6.8* | 260.3±3.5* |
| Mean food consumption | Week before pregnancy | 13.06 | 1.83E-04 | 15.6±0.4 | 13.3±0.4* | 13.7±0.0* |
| (g/day) | Pregnancy | 10.23 | 7.24E-04 | 21.4±0.4 | 17.8±0.9* | 19.3±0.0* |
| Mean food consumption | Week before pregnancy | 0.05 | 0.95 | 61.9±1.3 | 62.3±1.5 | 61.7±1.2 |
| (g/Kg bodyweight/day) | Pregnancy | 0.82 | 0.46 | 74.3±1.4 | 71.7±2.3 | 74.2±1.1 |
| Mean soln consumption | Week before pregnancy | 19.14 | 1.53E-05 | 24.9±1.2 | 14.5±0.7*# | 18.9±1.4* |
| (ml) | Pregnancy | 33.40 | 2.16E-07 | 45.0±2.7 | 21.8±1.7*# | 38.0±1.6 |
| Mean soln consumption | Week before pregnancy | 10.97 | 4.97E-04 | 98.5±3.6 | 68.2±3.4*# | 84.5±5.7 |
| (ml/Kg bodyweight/day) | Pregnancy | 33.56 | 2.07E-07 | 155.1±6.7 | 88.1±6.2*# | 146.0±5.8 |
| Offspring | ||||||
| Bodyweight (g) | PND1 | 5.8 | 9.08E-03 | 5.3±0.1 | 4.7±0.1* | 5.1±0.1 |
*p<0.05 compared to Con, #p<0.05 compared to Con-Pf.