Table 2. Results from Student's t-tests for all three group comparisons.
Comparison | Probe-set ID | t-statistic | p-value | FDR q-value | Log2 (FC) | Accession Number | Gene | Description |
Nic vs. Con | 10868302 | 3.97 | 2.20E-03 | 0.24 | −0.50 | AY539927 | LRRGT00176 mRNA | - |
Nic vs. Con-Pf | 10727717 | 4.33 | 1.79E-03 | 0.26 | 1.44 | NM_153626 | Npas4 | neuronal PAS domain protein 4 |
10886031 | 5.80 | 3.81E-05 | 0.04 | 0.98 | NM_022197 | Fos | FBJ osteosarcoma oncogene | |
10899387 | 5.02 | 5.26E-04 | 0.17 | 0.97 | NM_024388 | Nr4a1 | nuclear receptor subfamily 4, group A, member 1 | |
10832802 | 6.39 | 1.29E-05 | 0.03 | 0.92 | NM_053633 | Egr2 | early growth response 2 | |
10904511 | 6.61 | 3.33E-05 | 0.04 | 0.85 | NM_019361 | Arc | activity-regulated cytoskeleton-associated protein | |
10868940 | 3.97 | 1.32E-03 | 0.23 | 0.76 | NM_031628 | Nr4a3 | nuclear receptor subfamily 4, group A, member 3 | |
10806585 | 5.68 | 4.57E-05 | 0.05 | 0.65 | NM_021836 | Junb | jun B proto-oncogene | |
10732652 | 4.62 | 3.58E-04 | 0.15 | 0.64 | NM_053769 | Dusp1 | dual specificity phosphatase 1 | |
10844339 | 5.48 | 1.05E-04 | 0.09 | 0.63 | NM_145677 | Slc25a25 | solute carrier family 25 | |
10940628 | 4.16 | 1.00E-03 | 0.22 | 0.57 | NM_001013146.1 | Fosb | Rattus norvegicus FBJ osteosarcoma oncogene B (Fosb) | |
10940647 | 4.18 | 1.01E-03 | 0.22 | 0.56 | NM_012954.1 | Fosl2 | Rattus norvegicus fos-like antigen 2 (Fosl2) | |
10834031 | 7.77 | 1.25E-06 | 7.80E-03 | 0.51 | NM_001079893 | Dusp14 | dual specificity phosphatase 14 | |
Con vs. Con-Pf | 10899387 | −12.32 | 2.94E-09 | 1.49E-05 | 1.44 | NM_024388 | Nr4a1 | nuclear receptor subfamily 4, group A, member 1/ |
10832802 | −9.06 | 3.07E-07 | 2.27E-04 | 1.22 | NM_053633 | Egr2 | early growth response 2 | |
10727717 | −3.43 | 6.01E-03 | 1.29E-01 | 1.16 | NM_153626 | Npas4 | neuronal PAS domain protein 4 | |
10868940 | −5.73 | 3.94E-05 | 8.09E-03 | 1.11 | NM_031628 | Nr4a3 | nuclear receptor subfamily 4, group A, member 3 | |
10904511 | −9.25 | 2.55E-07 | 2.10E-04 | 1.10 | NM_019361 | Arc | activity-regulated cytoskeleton-associated protein | |
10886031 | −6.68 | 9.74E-06 | 2.88E-03 | 1.07 | NM_022197 | Fos | FBJ osteosarcoma oncogene | |
10806585 | −7.30 | 1.84E-06 | 8.50E-04 | 0.79 | NM_021836 | Junb | jun B proto-oncogene | |
10940628 | −5.45 | 6.88E-05 | 1.30E-02 | 0.78 | NM_001013146.1 | Fosb | Rattus norvegicus FBJ osteosarcoma oncogene B (Fosb) | |
10760080 | −11.43 | 4.83E-09 | 1.49E-05 | 0.76 | NM_001002829 | Rasl11a | RAS-like family 11 member A | |
10940647 | −5.35 | 8.89E-05 | 1.49E-02 | 0.74 | NM_012954.1 | Fosl2 | Rattus norvegicus fos-like antigen 2 (Fosl2) | |
10872626 | −10.37 | 1.86E-08 | 3.44E-05 | 0.70 | NM_153727 | Gpr3 | G protein-coupled receptor 3 | |
10732652 | −5.42 | 5.86E-05 | 1.14E-02 | 0.70 | NM_053769 | Dusp1 | dual specificity phosphatase 1 | |
10844339 | −5.94 | 2.79E-05 | 6.08E-03 | 0.67 | NM_145677 | Slc25a25 | solute carrier family 25 | |
10834031 | −8.78 | 2.37E-07 | 2.10E-04 | 0.66 | NM_001079893 | Dusp14 | dual specificity phosphatase 14 | |
10716080 | −11.05 | 4.04E-08 | 5.97E-05 | 0.62 | NM_133578 | Dusp5 | dual specificity phosphatase 5 | |
10768332 | −11.81 | 6.03E-09 | 1.49E-05 | 0.61 | NM_053453 | Rgs2 | regulator of G-protein signaling 2 | |
10863676 | −6.15 | 2.26E-05 | 5.39E-03 | 0.61 | NM_019137 | Erg4 | early growth response 4 | |
10815763 | −5.36 | 7.19E-05 | 1.33E-02 | 0.57 | NM_001107679 | Tiparp | TCDD-inducible poly(ADP-ribose) polymerase | |
10896793 | −6.80 | 9.41E-06 | 2.88E-03 | 0.57 | NM_023985 | Trib3 | tribbles homolog 1 (Drosophila) | |
10719432 | −5.45 | 1.10E-04 | 1.60E-02 | 0.56 | ENSRNOT00000022556 | Fosb | FBJ osteosarcoma oncogene B | |
10701846 | −14.66 | 6.90E-06 | 2.32E-03 | 0.56 | NM_053698 | Cited2 | p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | |
10800919 | −8.48 | 8.32E-07 | 4.73E-04 | 0.55 | NM_012551 | Egr1 | early growth response 1 | |
10792035 | −7.39 | 5.87E-06 | 2.28E-03 | 0.55 | NM_022199 | Dusp4 | dual specificity phosphatase 4 | |
10780205 | −4.99 | 2.18E-04 | 2.44E-02 | 0.51 | NM_031056 | Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | |
10710028 | −8.00 | 7.58E-07 | 4.67E-04 | 0.51 | NM_024362 | Arntl | aryl hydrocarbon receptor nuclear translocator-like | |
10833811 | 4.32 | 9.86E-04 | 5.84E-02 | -0.56 | - | - | - |
Shown are all genes reaching significance at p<0.01 and |FC≥0.5| ordered by FC. In bold are those genes that are up-regulated in both the Nic vs. Con and Con-Pf vs. Con comparisons.