Figure 2. Colonic miRNA expression levels are modulated in villin-hPepT1 and FVB WT mice with and without DSS.
miRNAs expressed with the a p-value of <0.01 and signal >500 in microRNA microarray were analyzed by qRT-PCR (Fig. 2A). miRNA 3077, miRNA 1934, miRNA 2145 were not associated with any target mRNAs so these three miRNAs were excluded from further analysis (Fig. 2B) and the mature mmu-miR-1937a, mmu-miR-1937b, and mmu-miR-1937c are fragments of tRNA (www.mirbase.org) so we eliminated these from further analyses (Fig. 2C). Difference in miRNA expression noted as * p<0.05, ** p<0.001 and *** p<0.0001. Values represent means ± SEM of n = 6/group.