Table 1. DAVID functional annotation clustering of villin-hPepT1 and FVB WT at the basal level.
| Annotation cluster | Enrichment score | Enriched functional group gene annotation/function | Total gene count |
| 1 | 4.77 | Transcription and Transcription regulation | 144 |
| Nucleus | 128 | ||
| DNA – binding | 54 | ||
| 2 | 3.31 | Isopeptide bond | 18 |
| Ubl conjugation | 27 | ||
| Cross-links: glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) | 10 | ||
| 3 | 2.17 | Nucleotide-binding | 64 |
| atp-binding | 51 | ||
| Transferase | 53 | ||
| Kinase | 28 | ||
| Domain: protein kinase | 22 | ||
| Binding site: ATP | 24 | ||
| Nucleotide phosphate-binding region: ATP | 35 | ||
| Serine/threonine-protein kinase | 17 | ||
| Active site: protein acceptor | 24 | ||
| 4 | 2.05 | Golgi apparatus | 28 |
| Topological domain: Lumenal | 20 | ||
| glycosyltransferase | 11 | ||
| Signal-anchor | 17 | ||
| 5 | 2 | Domain:W2 | 5 |
| Initiation factor | 4 | ||
| Protein biosynthesis | 5 | ||
| 6 | 1.83 | Repeat: LDL-receptor class B1–20 | 71 |
| Repeat: LDL-receptor class A1–8 | 27 | ||
| Domain: EGF-like1–8 | 45 | ||
| Domain: EGF-like 2;calcium binding | 3 | ||
| Endocytosis | 6 | ||
| Short sequence modif: Endocytosis signal | 3 | ||
| 7 | 1.56 | Nucleotide binding | 6 |
| P-Loop | 6 | ||
| GTP binding | 4 | ||
| 8 | 1.37 | Calcium and calcium binding region 1–2 | 41 |
| Domain: EF-hand 1–3 | 24 | ||
| 9 | 1.35 | Cell division | 13 |
| Cell cycle | 19 | ||
| Mitosis | 8 | ||
| 10 | 1.12 | Short sequence motif: DEAD box | 4 |
| Short sequence motif: Q box | 4 | ||
| Domain: Helicase C-terminal | 6 | ||
| Domain: Helicase ATP binding | 6 | ||
| Helicase | 6 | ||
| 11 | 1.1 | Domain: WW 1–3 | 9 |
The common proteins were clustered into 30 groups, but based on enrichment score >1.0. 11 groups were considered to be the potential targets with a total of 1100 genes.