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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: J Ultrasound Med. 2013 Sep;32(9):1593–1600. doi: 10.7863/ultra.32.9.1593

Table 4.

Predictive Efficiency of First-Trimester Parameters for Early Pre-Eclampsia

Marker AUC
(95% CI)		 Sensitivity
10% FPR		 Sensitivity
20% FPR
Maternal Characteristics Alone 0.71
(0.54-0.88)		 55% 58%
ADAM12 Alone 0.63
(0.46-0.80)		 22% 30%
PAPP-A Alone 0.55
(0.38-0.71)		 16% 22%
Uterine Artery Doppler Alone 0.60
(0.44-0.75)		 10% 38%
ADAM12 +PAPP-A + Uterine Artery
Doppler Alone 		0.65
(0.48-0.82)		 35% 46%
Maternal Characteristics + ADAM12 0.77
(0.620.93)		 54% 62%
Maternal Characteristics + PAPP-A 0.75
(0.60-0.90)		 54% 54%
Maternal Characteristics + Uterine
Artery Doppler 		0.71
(0.53-0.90)		 54% 62%
Maternal Characteristics + ADAM12 +
PAPP-A 		0.78
(0.63-0.93)		 54% 62%
Maternal Characteristics + ADAM12 +
Uterine Artery Doppler 		0.77
(0.61-0.93)		 54% 62%
Maternal Characteristics + ADAM12 +
PAPP-A + Uterine Artery Doppler 		0.77
(0.62-0.93)		 54% 62%
*

Maternal characteristics: African American race and history of chronic hypertension