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An example of the predicted improvement factor for Angiotensin II in the simple background experiment using A) CHCA and B) DHB is shown. The highest improvement factor is achieved at exogenous concentrations close to the LODorig of the target peptide for both CHCA (0.67 LODorig) and DHB (1.46 LODorig) matrices. Due to the increase in the standard deviation of the measurements, the improvement factor decreases at higher exogenous concentrations.
