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. Author manuscript; available in PMC: 2014 Feb 20.
Published in final edited form as: Anal Chem. 2012 Aug 28;84(18):7626–7632. doi: 10.1021/ac301423f

Table 2.

The optimal exogenous concentrations and improvement factors for complex background experiment using CHCA matrix averaged over triplicate independent experiments. On average, the optimal exogenous concentration required for predicted maximum LOD improvement factor is close to 2 LODorig.

Peptide Local maximum exogenous concentrations (C/LODorig) Local maximum improvement factors (LODorig/LODC)
Angiotensin I 2.57 ± 0.31 3.05 ± 0.81
Angiotensin II 0.71 ± 0.31 1.85 ± 0.85
β-Amyloid (1-15) 3.15 ± 2.59 1.59 ± 0.48
All three peptides 2.14 ± 0.74 2.16 ± 0.45