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. 2014 Feb 19;9(2):e89026. doi: 10.1371/journal.pone.0089026

Figure 2. Effects of aspirin and PNP on the liver weight to body weight ratio and oxidative stress related parameters.

Figure 2

Panel A. Measurement of liver weight to body weight ratio. Panel B. Measurement of the ferric reducing antioxidant Power (FRAP). CONT: normal mice group, PNP: mice treated with only PNP, ASA: mice administrated with aspirin, ASA+PNP: mice treated with PNP after aspirin intoxication. Panel C. Effect of Aspirin and PNP on Glutathione (GSH & GSSG) activities in liver tissue. GSH to GSSG ratio. Panel D. Effect of Aspirin and PNP on Glutathione (GSH & GSSG) activities in spleen tissue. GSH to GSSG ratio. Cont: normal mice, PNP: mice treated with only PNP, ASA: mice intoxicated with aspirin, ASA+PNP: mice treated with PNP after aspirin intoxication. ASA+VitC: mice treated with vitamin C after aspirin intoxication. “a” indicates the significant difference between the normal control and ASA intoxicated groups, and “b” indicates the significant difference between ASA intoxicated (toxin) and PNP post-treated groups. Each column represents mean ± SD, n = 6; (Pa<0.05, Pb<0.05).