Figure 5. Western blot analysis of different mitogen activated protein kinases (MAPKs) in liver tissue homogenates.

phosphorylated p38 (phospho- p38) and total p38 MAPK, phosphorylated JNK MAPK (phospho-JNK MAPK) and total JNK MAPK. β actin was used as an internal control. Data represent the average ± SD, n = 6; (P^a<0.05, P^b<0.05). Cont: normal mice, PNP: mice treated with only PNP, ASA: mice intoxicated with aspirin, ASA+PNP: mice treated with PNP after aspirin intoxication. ASA+VitC: mice treated with vitamin C after aspirin intoxication. “a” indicates the significant difference between the normal control and ASA intoxicated groups, and “b” indicates the significant difference between ASA intoxicated (toxin) and PNP post-treated groups. Each column represents mean ± SD, n = 6; (P^a<0.05, P^b<0.05).