Table 4. Effect of Aspirin and PNP on lipid peroxidation and protein carbonylation in spleen tissue.
Parameters | Normal | PNP | ASA | ASA+PNP | ASA+VitC |
MDA(nmol/mg protein) | 0.75±0.04 | 0.69±0.038 | 2.92±0.12a | 1.24±0.061b | 1.59±0.07b |
Protein carbonylation(nmol/mg protein) | 5.12±0.20 | 4.95±0.18 | 6.38±0.34a | 5.75±0.30b | 6.11±0.33b |
Values are expressed as mean ± SD, n = 6.
values differs significantly from normal control (Pa<0.05);
values differs significantly from toxin(ASP) control (Pb<0.05).