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. 2014 Mar;28(3):1375–1385. doi: 10.1096/fj.13-240507

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Figure 7. — Imaging PKA activity in neuronal processes. Grayscale fluorescence image shows a segment of the apical dendrite and associated spines of a pyramidal neuron expressing the GAkdYmut sensor. Traces show the variations of GAkdYmut fluorescence intensity elicited by CRF (250 nM) and FSK (13 μM) in RPIs including the dendritic shaft and 3 spines (indicated by arrows on the grayscale image). Pseudocolor images of the same field at indicated time points illustrate GAkdYmut responses on drug application.