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. 2014 Feb 19;9(2):e89326. doi: 10.1371/journal.pone.0089326

Figure 7. Cdk4 protein expression in LPS-activated Runx1t1 knockdown BV2 microglia.

Figure 7

A–B. Western blot analysis shows that Cdk4 protein expression is upregulated in LPS-treated BV2 microglial cells (A–B). However, a significant downregulation of Cdk4 protein expression is detected in LPS-treated BV2 microglia after knockdown of Runx1t1 (A–B). The significant difference between the groups (scrambled siRNA vs scrambled siRNA +LPS, Runx1t1 siRNA vs Runx1t1 siRNA+LPS and scrambled siRNA +LPS vs Runx1t1 siRNA+LPS) are indicated by *p<0.05, **p<0.01(n = 3).