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HDACi treatment increased acetyl-histone H3 staining in microglial cells(C,D) when compared to control cells (A,B). Further, knockdown of Runx1t1 markedly increased acetyl-histone H3in microglial cells treated with or without LPS (I–L) when compared to scrambled siRNA transfected cells (E–H). Scale bars: 50 µm.
