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. 2014 Feb 19;9(2):e89326. doi: 10.1371/journal.pone.0089326

Figure 13. NO productionin BV2 microglia transfected with Runx1t1 siRNA or treated with HDACi.

Figure 13

A–B. Nitric oxide (NO) assay analysis indicates that nitrite level is significantly increased in LPS-treated BV2 microglial cells and is brought down to near base level either by Runx1t1 siRNA knockdown(A) or by HDACi treatment (B). Significant differences between groups (scrambled siRNAvs scrambled siRNA +LPS, scrambled siRNA +LPS vs Runx1t1 siRNA+LPS, control vs LPS, control vs HDACi+LPS, LPS vs HDACi, LPS vs HDACi+LPS) are indicated by *p<0.05, **p<0.01 (n = 3).