Table 3. Parameters of energy balance in juvenile (4- to 5-wk-old) and adult (12- to 14-wk-old) mdx and control mice.
Group | Juvenile | Adult | P | ||||||||||
mdx | Control | mdx | Control | A×G | A | G | |||||||
N | 8 | 8 | 9 | 12 | |||||||||
Intake | |||||||||||||
24 h (kcal/d)1 | 11.0±0.7 | 11.3±0.4 | 11.7±0.6 | 10.9±0.4 | NS | NS | NS | ||||||
Expenditure | |||||||||||||
24 h (kcal/d)1 | 11.0±0.5 | 10.5±0.3 | 10.4±0.4 | 10±0.3 | NS | NS | 0.03 | ||||||
12 hdark (kcal/12 h)1 | 5.9±0.5 | 5.7±0.2 | 5.5±0.3 | 5.6±0.2 | NS | NS | NS | ||||||
12 hlight (kcal/12 h)1 | 5.1±0.2 | 4.8±0.1 | 4.9±0.2 | 4.4±0.1 | NS | 0.04 | <0.001 | ||||||
Resting (kcal/d)1 | 9.0±0.4 | 8.4±0.2 | 6.5±0.3 | 6.1±0.2 | NS | <0.001 | 0.01 | ||||||
Balance | |||||||||||||
24 h (kcal/d) | 0.44±0.16* | 1.03±0.16 | 0.74±0.15 | 0.77±0.13 | 0.07 | NS | 0.05 | ||||||
RQ | |||||||||||||
24 h | 0.91±0.02 | 0.92±0.02 ‡ | 0.95±0.01 | 0.96±0.01 | NS | 0.004 | NS | ||||||
12 hdark | 0.97±0.02 | 0.97±0.02 | 0.99±0.02 | 0.99±0.01 | NS | NS | NS | ||||||
12 hlight | 0.84±0.02 | 0.87±0.02 ‡ | 0.92±0.02 | 0.93±0.01 | NS | <0.001 | NS |
EE, energy expenditure; RQ, respiratory quotient.
Values are least square means adjusted for differences in FFM and fat mass±SE. Where interactions are ≤0.1:
*significant genotype effect at the same age.