Figure 4. Effect of DFO on the UUO-induced acceleration of TGF-β-Smad pathway.
(A) Upper panels: representative immunoblotting for TGF-β1 expression. Lower panels: quantitative evaluation of TGF-β1 protein expression at day 7. Results are expressed as the mean ± SEM. *P<0.05, **P<0.01. n = 12 in each group. (B) Upper panel: representative western blots of phopsho-Smad3, total-Smad3, and tubulin. Lower panel: quantification of western blots. Results are expressed as the mean ± SEM. *P<0.05, **P<0.01. n = 12 per group.