Table 1. Body weight, kidney weight, hemoglobin content, and kidney iron content in mice, 7 days after surgery.
Sham with vehicle (n = 18) | Sham with DFO (n = 14) | UUO with vehicle (n = 15) | UUO with DFO (n = 15) | |
Body weight (BW) (g) | 26.8±0.8 | 25.9±0.3 | 26.6±0.5 | 26.6±0.8 |
Right kidney weight (RKW) (mg) | 136±4## | 137±2## | 155±3** †† | 158±3** †† |
RKW to BW ratio | 5.2±0.1## | 5.3±0.1## | 6.1±0.1** †† | 6.2±0.2** †† |
Left kidney weight (LKW) (mg) | 135±5## | 131±3# | 116±1** † | 134±5# |
LKW to BW ratio | 5.0±0.1# | 5.0±0.1# | 4.6±0.1* † | 5.2±0.2## |
Hemoglobin (g/dL) | 13.8±0.3 | 12.8±0.1 | 13.1±0.3 | 13.6±0.2 |
Hematocrit (%) | 42.3±0.8 | 39.7±0.4 | 40.3±1.0 | 41.3±0.7 |
Left kidney iron (µg/g kidney tissue) | 5.9±0.6# | 4.8±0.7## | 9.0±1.2* †† | 4.9±0.6## |
Data are the mean ± SEM, n = 14–18, as indicated.
*P<0.05,
**P<0.01 vs. sham with vehicle;
P<0.05,
P<0.01 vs. sham with DFO;
P<0.05,
P<0.01 vs. UUO with vehicle.