Table 1.
Fe and Thyroid Hormone Status of Rat Dams
Characteristic | Control | FeD | 1 ppm PTU | 3 ppm PTU | FeD/1 ppm PTU | FeD/3 ppm PTU | 10 ppm PTU |
---|---|---|---|---|---|---|---|
Body weight, g | 281 ± 14.7 | 295 ± 8.7 | 275 ± 2.9 | 317 ± 12.2 | 310 ± 13.5 | 319 ± 5.8 | 285 ± 9.1 |
Hemoglobin, g/L | 143 ± 4.1ab | 115 ± 8.0b | 155 ± 3.7a | 142 ± 4.0ab | 126 ± 10.4ab | 111 ± 9.4b | 146 ± 11.2ab |
Serum Fe, μg/mL | 3.6 ± 0.48a | 0.93 ± 0.03b | 4.1 ± 0.27a | 4.1 ± 0.50a | 1.1 ± 0.18b | 0.95 ± 0.12b | 4.0 ± 0.51a |
Serum TT4, ng/mL | 35.9 ± 3.2a | 42.9 ± 5.1a | 29.2 ± 6.0ab | 15.2 ± 3.9bc | 30.4 ± 3.6a | 25.2 ± 5.2a | 5.5 ± 1.7c |
Serum TT3, ng/dL | 77.6 ± 7.1 | 87.3 ± 5.5 | 91.6 ± 9.2 | 80.2 ± 15.5 | 105 ± 7.0 | 100 ± 10.3 | 125 ± 24.8 |
Data are presented as the mean ± SEM (n = 5). Within a specific row, means not sharing a common letter superscript are significantly different by one-way ANOVA and Tukey's multiple comparison test (P < .05). If the lettered superscripts are the same, no significant differences were observed between groups.