Figure 21. Number of 3did domain-pairs [19] found in the top 100 domain-pairs for Yeast and for Human.

Without Pfam-B domains, both oA and OA still have more 3did domain-pairs in their top 100 than both Oa and oa. However, in contrast to Figure 17, now OA has more 3did domain-pairs than oA. This is because there are no promiscuous Pfam-B domains to cloud OA’s ranking.